Abstract Search

ea0005oc11 | Cardiovascular Endocrinology | BES2003

Characterisation of the metabolic syndrome in the stroke prone spontaneously hypertensive rat and the contribution of the Y chromosome

Strahorn P , Graham D , Champange B , Charchar F , Crawford L , Sattar N , Dominiczak A

Objective: The spontaneously hypertensive stroke prone rat (SHRSP) is a model of insulin resistance and dyslipidemia. Feeding a 60% fructose diet exaggerates these phenotypes. The Y chromosome may influence lipid levels in the spontaneously hypertensive rat (SHR). Therefore we aim to characterise the metabolic syndrome using in vivo and dyslipidemic phenotpyes in the SHRSP and examine the contribution of the Y chromosome.Methods: SHRSP and WKY Y consomic strains (SP...

0 shares

ea0003oc6 | Genetics: New Insights into Endocrine Disease | BES2002

Y chromosome consomic strains and metabolic syndrome in the stroke prone spontaneously hypertensive rat

Strahorn P , Graham D , Crawford L , Morton J , Sattar N , Dominiczak A

Objective: The spontaneously hypertensive stroke prone rat (SHRSP) is a model of insulin resistance and dyslipidemia. Feeding a 60% fructose diet exaggerates these phenotypes. It has been suggested that the Y chromosome may influence lipid levels in the spontaneously hypertensive rat (SHR). Therefore we examined the effects of Y chromosome on lipid phenotypes in the SHRSP after fructose feeding.Design and Methods: The S.W. Y consomic strain was construc...

0 shares

Endocrine Abstracts

Characterisation of the metabolic syndrome in the stroke prone spontaneously hypertensive rat and the contribution of the Y chromosome

Y chromosome consomic strains and metabolic syndrome in the stroke prone spontaneously hypertensive rat

BiosciAbstracts